Monday, February 28, 2011

Heart drug from Nuvelo buyer rejected - San Francisco Business Times:

burwellmitubaes1369.blogspot.com
said the FDA asked the companuy to do additional clinical studies on itslead drug, Gencaro. In sayingt that Gencaro didn’t provs it was effective, the FDA also questioned the integrit yof Arca’s trial data based on an audit of some clinical trialk sites. The FDA, however, said it had not reviewed several amendments that Arca filed in May to its new drug Gencaro — the centerpiece of a reverse mergedr in January between Arca and Nuvelo had been shelved by BMY) in 1999 after it didn’t show a significant statistical difference compared to a Yet researchers later discovered that some of the tria enrollees were hyper-responsive to the drug due to common genetic variations.
Arca said it and had developes an accompanying genetic test to weed out patients who had that The reverse mergerwith Nuvelo, which itseltf had stalled after its clot-buster drug alfimepraser failed a late-stage clinical triap in December 2006, made Arca publicly traded. The deal also gave Arca accessto Nuvelo’s remaining cash. Arca (NASDAQ: ABIO), base d in Broomfield, Colo., northh of Denver, is led by President and CEO Richard a Santa Cruz resident and former chieof Fremont’s Scios Inc. Scios and its ill-faterd heart failure drug Natrecor were sold six years ago tofor $2.
3

Saturday, February 26, 2011

CoBiz posts $16M Q2 loss, begins stock sale - The Business Review (Albany):

goods-depreciating.blogspot.com
million, or 72 cents per share, in the secons quarter, as the weak economy continued to exact a toll on the officialssaid Monday. The loss compare s with a profitof $4.2 million, or 18 centsw per share, in the same quarter a year Denver-based CoBiz (NASDAQ: owns and Arizona Business The latest quarter’s results includw a $35.1 million pre-tax provision for loan and credit losses, or 150 percent of net charge-offds — which were $23.3 million — for the period. “We continue to take a conservativde posture in our provisioning forloan losses,” Chairman and CEO Steve Bangert said in a statement.
“Our second quarter provision brings our allowance to loan ratio tonearlg 3.9 percent, one of the strongest in the industry. Whiled I remain confident in oursenior management’s ability to effectivelyy respond to the current credit obstacles, we felt it was prudenf to continue building the allowance givenb the uncertainty in the economy.” Nonperforming assets endedx the quarter at $93.9 million, or 3.7 percenty of total assets, up from $52.5r million or 2 percent of total assets on March 31. Separatelty on Monday, CoBiz said it had beguj a sale ofabout $45 million of its commonb stock.
It will use the proceedz for general corporate including supporting the capital needs of itsbank subsidiary, expandingv operations, possible acquisitions and workinb capital needs. Last week, CoBiz announced it had hire d Colorado and Arizonamarket , to oversee banking operations in each “We remain focused on building our franchise duringv these challenging times and want to ensure we are positionedx to take advantage of unique market opportunitiesz that we expect will presengt themselves,” Bangert said.
“To that end, we recently announced the hiring of Colorado and Arizonwa market presidents who will oversee all bankinhg operations in theirrespective markets, providew direction for future growth and free up some of our existintg resources to focus on high quality business development We will also continue to dedicate appropriate resources through our Special Assets Group to addresz resolution of problem loans.

Wednesday, February 23, 2011

Report: Fewer remodel homes, but more want to - Tampa Bay Business Journal:

http://faylicity.com/book/book1/fstciti.html
The report finds that remodelinyg permit activity was down 20 percent during thefirst quarter, year-over-year. the report also found a 5 percent increase in the numbefr of homeowners who said they will probablg remodel in the next12 It’s the first increase since 2007, when more than 90 perceny of homeowners said they were thinking of And for those thinking about it, there’s another bright spot, accordinyg to the report. The cost of remodelinv is 20 percent less than it wasin 2006. Eight-two percenr said the cost to remodel is theirbiggestr concern.
Twelve percent planned to use economical materials whenthey remodel, while 12 percent said they plan to use expensivse materials, and the remaining 76 percent will use standard-priceed materials. Eighty-nine percent are changing their remodeling planx because of the currenteconomic recession.

Monday, February 21, 2011

China Ministry Regrets Huawei's Withdrawal Of Plan To Buy 3Leaf Assets - Wall Street Journal

concrete roofs


Malaysia Star


China Ministry Regrets Huawei's Withdrawal Of Plan To Buy 3Leaf Assets

W »

Friday, February 18, 2011

GM to identify 14 plant closures but probably not Wentzville - The Business Journal of Milwaukee:

rubber roofs
The announcement could coincidewith GM’s bankruptch filing, an unnamed source told The Associated Four vehicle assembly plants, along with parte stamping, engine and transmission factories, will be shuttered, the AP reported. GM’as plant in Wentzville, Mo., could be spares because it’s the only plant where Chevrolet Express and GMC Savans vansare made, said Haig an auto industry analysgt with . “I would think that they woulsd keep thatproduct going,” he “In the long run they are commercialp vehicles and there is use for them.
They are used for constructionj jobs, fleets for major utilityy companies, independent contactors and electricians andshuttle vehicles.” If GM were to move Wentzville’s operationse to another plant, it woulfd have to redesign the vans to fit the platform of othet vehicles because the vans do not share partw with light trucks, for example, Stoddard Robert Wheeler, a spokesmaj for GM’s Wentzville plant, said he does not know whichg facilities will be closed. “Unfortunately, we will likely hear this news at the same he said.
A representative from United Auto WorkerLocal 2250, whichg represents 1,700 workers at the Wentzville plant, was not immediatelgy available to comment because unionn members were busy votinv Thursday on UAW contract concessions.

Wednesday, February 16, 2011

Apple, Google, Microsoft, others may be under scrutiny for hiring practices - St. Louis Business Journal:

dudorovanaapyh.blogspot.com
"Guys, we have a problem," Ballmer says. "Somer of our best employees are job-hoppinh like locusts, feasting on the higherr wages and better perks from ourcompetitors -- that would be you. Now I know we'ved gone on plenty of raidingbparties ourselves. But it's just time to stop the madness. I'mn ready to reach a gentlemen's agreement not to poacbh your superstarsif you'll do likewise." Jobs doesn'r hesitate. "I'm tired of paying moving expenses from And it's getting old hearing some of my employee whining about how great the perks were when they were at I'm all for a change." The Google guys speaj in unison: "Count us in!
" The specifixc meeting we described, of course, took placw only in our imagination. But the reportedluy wants to knowif tech's big boys really have been colluding to keep their top talenf from jumping ship. The and , citing unnamed sources, reporgt that the investigation is preliminary and focusesw ona who’s who of Silicon Valley tech companies includingy search giant Google, its rivaol , iPhone maker Apple and biotech firm . reports that the Justice Department has issued formal requestsd for documentsfrom “at leasr a dozen” tech companies.
“If they are (colluding) as is being investigatedd … then it is a serious potential anti-trust said Albert Foer, president of the Americajn Antitrust Institute. Collusion between the companies could depress wages. In 2001, Supreme Court nominee Judge Sonias Sotomayor wrote an appeals court opinion siding with a group of oil geologists and petroleumk engineers who claimed and other oil companieds were colluding inhiring decisions.
Collusion coulcd also damage the innovation for which Silicon Valletyis famous, by keeping talented peoplew from moving to new companiew and bringing with them fresh “One of the things that feeds innovatio n is people moving around,” Foer “Whereas Silicon Valley is famous for people movinv around … that practice wouldc be tailing off or ended by such an between companies not to poach talent.
While the tech worled may be famous for talented people jumping from companygto company, those jumpds haven’t always been exactly amicable, and tech firmd often tie top talent to contracts that restrict them from goingv to work for the competitiomn for set periods of time. In fact, the moves of taleny from one tech behemoth to anothedr have sometimes landed in as when former Microsoftemployewe Kai-Fu Lee went to work for Google, John Oatesa points out at . So it’ds not out of the real of reason to imagine tech bossee looking to keep top talent from moving without the hasslesz ofcourt fights. But already, the federal probse is drawing skepticism inthe blogosphere.
Larry writing on ZDNet’s blog, callsz the probe a fishing expeditionwith “waste of time writtenj all over it.” As Dignan points out, it’s prettyu unlikely that there are any smoking gun agreementas lying around the offices of the tech and he adds: “Top talent isn’t that restricted. Google execxs go to Facebook. They go to AOL. Yahok execs go to Microsoft. Microsoft execs go to Google. In you can make quite a career just hopping between thoswaforementioned companies.” The probe comes as the government is steppinf up scrutiny of the often-coz relationships in the high-tech sector.
Assistan Attorney General Christine Varney, who is in charge of the DOJ'ss Antitrust Division, that the department would be taking a closet look at activities in the The Federal Trade Commission to Google earlier in the year becauss ofantitrust concerns. FTC questions concerned the overlap of directorsa between Google andGenentech — Googler boss Eric Schmidt sits on the Apple Inc. boarx with Art Levinson, who was CEO of Genentech at the Regulators also called a halt to an advertisingb revenue sharing deal Google madewith Yahoo.

Sunday, February 13, 2011

Beyond green - San Francisco Business Times:

http://canberrasight.com/why-the-poppy-must-never-wither-as-the/
The leader of the design firm that landesd on the Bay Area map in 1997 with the desighn ofthe then-revolutionary greenn Gap building at 901 Cherrgy St. in San Bruno is described as asustainabler guru, an environmental prophet, a green He is most famouw for co-authoring the environmental treatise “Cradle to Remaking the Way We Make which he describes as a “manifesto calliny for the transformation of humann industry through ecologically intelligent design.” Cradle to or C2C, has thousands of passionatr followers around the globe, including entire citiesz in the Netherlands that have adopted its goals as publicf policy.
Hollywood A-listers like Brad Pitt, Leonardo DiCaprio and Cameronn Diaz seekhis counsel. In the Bay McDonough’s firm is rapidly gaining traction not just for bookesand ideology, but also for corporater headquarters, hospitals and mixed-use developments. Two yearse after opening an office at 177Post St., the Va.-based McDonough + Partners is designing some of the biggesy and most complex projects in the Bay At Moffett Field in the South Bay, McDonoughh is part of a team designinh a 1.3 million-square-foot, 42-acre campus for , likely to be a $700 millionn development when completed. In San Francisco’s Mission Bay, the firm is workinb with on a $1.
6 billion 865,000-square-foot hospital for the Universit yof California, San Francisco. The firm’s San Francisco studio is also designinga 45,000-square-foot administrative buildingh for NASA Ames Researcgh Center at Moffett Field, a new San Francisco headquarterw for Norcal Waste and a pair of mixed-use condop and grocery store projects beinv developed by the , one at 1401 California St. on Nob Hill and one at 2001 Markeg St. in San Francisco’s Castro Director of PracticeKevin Burke, who splits his time betweebn Virginia and San said the burst of Bay Area assignmentsw has been satisfying.
“Ultimately we’re architects and we want to desigbbuildings — that’s what we really, reall y like to do, and that is how we give form to this philosophyy and these values,” said Burke. After a dozen yearws of shuttling back and forth between Virginiaz and theBay Area, the 15-person San Francisco office is now so busy that at any one time five or six more designere are here, according to David Johnson, who moveds over from Studios architecture in 2006 and heads the San Francisco Other new directors hired for the San Francisci office include Matthew Winkelstein from HOK and Jeffrety Till from .
“We still have more work in the Bay Area than we can delive r with the SanFranciscop office, so we have to be said Johnson. “What is great about San Franciscop is we have so many opportunities a 45 minutes carride away. And the range of projects we’re taking on locally is just amazing.” McDonough designs buildings that are enmeshed in The structures connect peoples to the outdoors with abundant use of natural They use energy from the sun directly througjh solar collection and passively through Theyuse on-site wetlands and botanical gardenx to recover nutrients from circulating water.
In the UCSF the “landscape is woven into the healint environment ofthe hospital” with nine garden s “responding to children, women, adults, a religious or spiritual experience. “Peoplew benefit from views of the sky, viewes of the landscape, close views and distant views. We’re wired for thosre things. That’s what makes us feel better,” said Burke. Johnsobn said the optimal McDonough building isa “synthetidc organism” in which all surfaces are where every inch of the envelop is producing oxygebn or energy, sequestering carbon or capturing “It’s a unique viewpoint of how hard can you get the surfacese to work, not how many LEED points you’r e going to get,” said Johnson.
“The new determination of qualitty is going tobe sustainability. It used to be, ‘Dio you have marble in your lobby? What is your elevatodr package?’ Now it’s ‘Is it a healthy environment for peoplee towork in?’ And one of the most sustainable things you can do as an architect is create something of beauty that people are going to enjoyh for generations. Why not put resources into buildings that are goingv to be around 100 years andbe loved?” Thesd days, William McDonough spendsa much of his time on his Cradl e to Cradle consultant business, McDonough Braungart Desigbn Chemistry, but still has a hand in McDonougnh + Partners design work.
Burkes said the design teams “looj for Bill’s engagement early on and conceptually.” He said McDonoug h “thinks metaphorically” and has a good sense of the ofthe project. McDonough weighsw in on a “broad approach of what systemsa and strategiesmight work,” Burke “You take the initial concept and give it back better than he ever Many of the McDonough Bay Area projects are in the earlyu stages. The two Pradio Group mixed-use developments are probably two years away fromreceivingf entitlements. The Norcal headquarters is stilp in a conceptual stage and is not tied to a particulard site atthis point.
“Norcalp asked us to create a vision for what it would look what it wouldfeel like,” said “We have been working with them on the highest-level visiobn for the company and what its goinb to take to achieves that, and that is a noble goal. Now therw are the realities of where is it goingto be, how big is it goinbg to be, how quickly it is going to come on line.” Johnsojn said McDonough is not afraid of losing its niche as more and more designers focus on sustainability. While developers are focusexd on meeting the basic criteria set fortuh bythe U.S.
Green Buildinvg Council, sustainable design is at its infant stage, especially in arease like health care, student industrial uses and largercommunitty planning. He said the goal is to expandr the ideals of Cradle toCradle “from the molecule to the to re-engage communities with their naturapl surroundings on all levels. “What we see is how far we haveto go, not how far we have said Johnson. Prado Group Principal Dan Safier said he picked McDonough because thefirm “has reall had international leadership in sustainable designh practices.
” “They have this high-quality team with a lot of experience, but they are a values-baseds firm that recognizes that an intelligentf environmental design strategy can create healthy urban living he said.

Friday, February 11, 2011

Breast-Feeding Supplies Win Tax Breaks From IRS - New York Times

http://aroundstars.com/r39/6/


CANOE


Breast-Feeding Supplies Win Tax Breaks From IRS

New York Times


The ruling, which will affect expenses incurred starting in 2010, will  »

Tuesday, February 8, 2011

Shia LaBeouf, Provoked by Gay Slur, Lands in Bar Fight - TheImproper.com

mesiaipuhuni1981.blogspot.com


TheImproper.com


Shia LaBeouf, Provoked by Gay Slur, Lands in Bar Fight

TheImproper.com


By TheImproper, February 6th, 2011 “Transformers” star Shia LaBeouf, by his own admission a nasty drunk, ended up in handcuffs with a fat lip after a fight ...



and more »

Sunday, February 6, 2011

Sales of Odyssey, Pilot, Ridgeline fall in May - Phoenix Business Journal:

llrx-royce.blogspot.com
Sales for the Ridgeline fell to 1,46 in May, down 56.6 percent from the 3,496 sold in May 2008. The pickupp has experienced some of the same struggles as otheer vehicles inits class. For the Ridgeline sales fell to 6,164 – down more than 63 perceng fromthe 17,152 sold in 2008. Odyssey sales fell slightly to a 2.9 percent drop from the 12,966 the Japanese automakerd reported for the minivan in May 2008. The Odyssey’as year-to-date sales slipped to 41,884, which represents a 29 percent decrease fromthe 59,987 sold in 2008. Saleas of the Pilot sport utilitty vehicle, which is also made at the plantin Lincoln, also dipped – falling 8.
9 percent to compared to the 8,449 sold in May of 2008. Year-to-date, sale s of the Pilot are down 28 percent. Overall saled for the entire Honda linedropped 39.2 percent for the

Thursday, February 3, 2011

Setting the barre high for spreading love of ballet - Business Courier of Cincinnati:

http://justauto-insurance.net/auto-insurance/connecticut-auto-insurance/
Since starting with the balletin Hauser, 32, has developed innovativs marketing strategies to bolster show attendancse - especially among the youngy professionals crowd. Hauser tackles everything from media interviewas to worldpremiere parties, packagee with local restaurants, e-mail blasts, advertising and direct mail for the ballett and its education department. A recent success is using the Web to tap into the YouTubw generationthrough "webisodes," mini Web-based dramatic episodesd promoting the ballet's performances. Victoria Morgan, artisti director, has seen the passion Hauser brings toher job.
"Since Barbara has been in charge of Morgan said, "the exposure and awarenesa for Cincinnati Ballet has broadened Her ability to connect the balleg to young and established the Hispanic and African-American communitieas has been impressive." A 1998 graduate of in communications, Hausefr started her career developing presss plans as account manager for a local She then joined the as director of The fun part of her job, Hauser said, is seeing the payoffd from her ideas. "It excites me that becausd of whatI do, more and more people are learninbg about ballet and having that cultural I work where the dancers rehearse, so I see theird blood, sweat and tears every day.
I love to help get an audiencesfor them." Hauser was a foundedr and is now an emeritus advisory committe e member of the 's One Worldr Wednesday program, where she helped attrac t up to 1,000 people to events. She chairs Second Sunday on Main, a festival in as well as YP Wired' s "Sounding Sessions," aimed at connecting young professionalk andbusiness leaders. A downtown resident, Hauserr grew up in Glendale, the youngest of threr girls. Stepping up and getting involved is part ofher "If there's something that interests me, I don'tt just want to hear about it, I want to It's really about connecting to the community.
" -- Lisa Courier Contributor

Tuesday, February 1, 2011

Mediation ordered on Veranda Park building - Triangle Business Journal:

zuloraxelewo.blogspot.com
U.S. Bankruptcy Judge Karen Jenneman on June 22orderesd Azzouz’s related firm and the bank to mediate theirf dispute on the partially built-out Offices at Veranda Park 1500 Azzouz on May 6 filed a voluntary Chapterr 11 bankruptcy petition in the Middle Distric t of Florida on behalf of , the entitt that owns his 55-unit building, just one day beforw it was scheduled for a foreclosure auction. VP Phaswe IV and other related companiesowed $15.
3 million to mortgage holder Fifthy Third Bank, which on May 7 filed a motionb asking the judge to either allows the foreclosure to continue or dismiss the bankruptcy Fifth Third claimed VP Phase IV filed the petitio just to stop the foreclosure and that the single-asset entity had no reasonable prospectz to reorganize under Chapter 11, the filing The decision by Jenneman allows the bankruptcy to continue, said VP Phasse IV attorney Norman Hull, owner of Orlando-based law firm Normab Linder Hull PA. Azzouz was directed to turn on utilitiex and provide proof of insurance to Fiftg Third on or beforeJune 29, as well as file his reorganizatioj plan by Aug. 5.
, Hull Azzouz could not be reachedfor Meanwhile, other buildings in the $1 billiom Veranda Park are facing severalo issues, including bankruptcy, pending foreclosure lawsuits and liens. Some of those include: The Residences at Veranda Park, a 157-unity residential condo building at 4000 Grande is scheduled to hit the foreclosure auctionh block July 14if Azzouz’s ownershio entity, VP Phase III LLC, doesn’rt pay $59.7 million owed to Wachovia Bank NA/Welle Fargo and Regions Bank. • Gene Chambers, Chapte 7 trustee for an individuapl who paida $41,424 deposit to VP Phase III for a residential condo, filed a breach of contracyt suit against VP Phase III on June 10.
The trustewe is attempting to recoverthat deposit, claimingh VP Phase III did not complete the condo by the promise d two-year time frame. • Commercial Ventures Orlando LLC, an Azzouz-owne entity that owns the CVS inVerandaa Park, filed a Chapter 11 bankruptcy petition on May 5. The entity owes a tota l of about $1.5 million to secured creditors andnearlyy $5,000 to unsecured creditors, court documents